HLA-DR antigen detection in giant cell lesions

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HLA-DR antigen detection in giant cell lesions.

Sixty-six giant cell lesions ranging from inflammatory to neoplastic were evaluated for HLA-DR antigens using formalin/paraffin tissue and a monoclonal antibody labelled by the avidin-biotin peroxidase. HLA-DR antigens were expressed in nearly all lesions, predominantly on round, macrophage-like cells. Granulomatous inflammatory lesions were generally more immunoreactive than non-inflammatory l...

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Isolation and purification of HLA-DR antigen from Daudi cell line by immunoaffinity chromatography

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The role of platelet microparticles in the production of antibodies from B lymphocytes against HLA-DR antigen in vitro

Background: Platelets can activate B cells and stimulate them for the production of antibodies. Since platelet microparticles (PMPs) originate from platelets, they may have the same virtue. In the present study, the effect of PMPs was investigated on the production of human leukocyte antigen (HLA)-specific antibody from B cells in vitro. Materials and Methods: In this experimental study, HLA-D...

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Expression of HLA-DR antigen in large bowel carcinoma.

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isolation and purification of hla-dr antigen from daudi cell line by immunoaffinity chromatography

introduction: the major histocompatibility complex (mhc) is a group of cell surface proteins that are essential for recognizing foreign molecules in human and other mammals. the physiologic function of mhc molecules is the presentation of peptides to t cells. in this study, we evaluated the purification of a class ii mhc molecule (hla-dr) from a human burkitt′s lymphoma cell line; daudi. materi...

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ژورنال

عنوان ژورنال: Journal of Oral Pathology and Medicine

سال: 1986

ISSN: 0904-2512,1600-0714

DOI: 10.1111/j.1600-0714.1986.tb00653.x